I agree with Chris, more information is essential to a good answer.
But, I will add that I have recently launched my own space using Lightroom Web-Module plug-ins that I got through The Turning Gate
website and I have been quite happy with the results. All told, I spent $15 and got really nice results with only some minor tweaking of the code in Dreamweaver.
The individual galleries are TTG Slimbox, the index is the TTG Autoindex, the main pages were laid out with TTG LR Pages (plus tweaking).
Now, this is just an online portfolio. I haven't tried to integrate shopping carts, payment systems, etc. . . Although, there are supposedly templates through TTG that allow that.